Palmitoyl pentapeptide-4 feem ntau yog siv los ua lub hauv paus gel rau kev tiv thaiv wrinkle firming cov khoom tu tawv nqaij
Palmitoyl pentapeptide-4 (pre-2006 palmitoyl pentapeptide-3) feem ntau yog siv los ua ib lub hauv paus gel rau kev tiv thaiv wrinkle firming cov khoom tu tawv nqaij.Nws yog los ntawm Spanish kev saib xyuas cov tawv nqaij cov khoom lag luam hauv xyoo 2000 raws li lawv tus kheej kev lag luam tu raws li cov khoom xyaw nquag, palmitoyl pentapeptide-4 yog peptide series ntawm kev siv ntxov tshaj plaws thiab feem ntau siv polypeptide, cov npe nrov hauv tsev thiab txawv teb chaws feem ntau yog siv los ua Qhov tseem ceeb muaj txiaj ntsig zoo nyob rau hauv kev tiv thaiv wrinkle firming tawv nqaij tu, nyob rau hauv ntau yam anti-wrinkle firming cov khoom tu tawv nqaij feem ntau tshwm sim hauv nws daim duab.Los ntawm kev nce collagen los ntawm dermis, nws tuaj yeem thim rov qab cov txheej txheem kev laus los ntawm kev tsim cov tawv nqaij los ntawm sab hauv.Kev cuam tshuam rau collagen, elastic fibers thiab hyaluronic acid nce, ua kom cov tawv nqaij noo noo cov ntsiab lus thiab noo noo tuav, ua kom tawv nqaij tuab thiab txo cov kab zoo.
Palmitoyl pentapeptide-4 (Pal-lys-thr-Lys-ser = Pal-KTTKS) muaj tsib amino acids txuas rau 16-carbon aliphatic chains los txhim kho cov permeability ntawm cov molecule los ntawm cov qauv lipid ntawm daim tawv nqaij.Qhov no yog margarine.Palmitoyl pentapeptide-4 yog tus xa xov peptide uas tswj hwm kev muaj peev xwm ntawm tes los ntawm kev cuam tshuam nrog lawv cov receptors tshwj xeeb.Lawv qhib cov noob koom nrog hauv kev txhim kho ntawm extracellular matrix thiab cell proliferation.Palmitoyl pentapeptide-4 muaj ib qho kev tiv thaiv-wrinkle thiab tawv-tightening nyhuv los ntawm activating tshiab synthesis ntawm macromolecules nyob rau hauv lub extracellular matrix.
Action mechanism
Cov kev tshawb fawb hauv vitro pom muaj 212% nce hauv hom I collagen synthesis, 100% rau 327% nce hauv hom IV collagen synthesis, thiab 267% nce hauv hyaluronic acid synthesis.Collagen kuv pom muaj nyob rau hauv ntau yam ntawm 19 hom collagen hauv lub cev.Yog li ntawd, ua kom tag nrho cov khoom ntawm collagen I muaj qhov cuam tshuam loj rau kev tsim kho ntawm daim tawv nqaij.Txoj kev tshawb fawb rau lub hlis hauv vivo pom qhov txo qis ntawm 17 feem pua hauv qhov tob ntawm cov kab zoo, 68 feem pua hauv thaj tsam ntawm cov kab sib sib zog nqus, 51 feem pua hauv thaj tsam ntawm cov kab nruab nrab, thiab 16 feem pua ntawm cov roughness ntawm tawv nqaij.
Post lub sij hawm: Apr-28-2023