Hauv daim ntawv no, ob qho tib si amino acids, glycine (Gly) thiab alanine (Ala), tau qhia.Qhov no feem ntau yog vim lawv tuaj yeem ua raws li cov amino acids hauv paus thiab ntxiv pab pawg rau lawv tuaj yeem tsim lwm hom amino acids.
Glycine muaj qhov tshwj xeeb qab zib, yog li nws lub npe lus Askiv los ntawm Greek glykys (qab zib).Suav txhais lus ntawm glycine tsis tsuas yog muaj lub ntsiab lus ntawm "qab zib", tab sis kuj muaj cov lus zoo sib xws, uas tuaj yeem hu ua tus qauv ntawm "kev ncaj ncees, kev ua tiav thiab kev zoo nkauj".Vim nws saj qab zib, glycine feem ntau yog siv los ua tus neeg sawv cev hauv kev lag luam zaub mov kom tshem tawm iab thiab ua kom qab zib.Lub sab saw ntawm glycine yog me me nrog tsuas yog ib qho hydrogen atom.Qhov ntawd ua rau nws txawv.Nws yog ib qho yooj yim amino acid tsis muaj chirality.
Glycine nyob rau hauv cov protein yog tus cwj pwm los ntawm nws qhov me me thiab yooj.Piv txwv li, peb-stranded helix conformation ntawm collagen yog tshwj xeeb heev.Yuav tsum muaj ib qho glycine rau txhua ob qhov seem, txwv tsis pub nws yuav ua rau muaj kev cuam tshuam ntau dhau.Ib yam li ntawd, kev sib txuas ntawm ob hom ntawm cov protein feem ntau xav tau glycine los muab kev hloov pauv yooj yim.Txawm li cas los xij, yog tias glycine hloov pauv tau txaus, nws qhov kev ruaj ntseg yuav tsum tsis txaus.
Glycine yog ib qho ntawm cov spoilers thaum lub sij hawm tsim α-helix.Yog vim li cas yog hais tias sab chains yog me me heev kom stabilize lub conformation ntawm tag nrho cov.Tsis tas li ntawd, glycine feem ntau yog siv los npaj cov tshuaj tsis haum.Cov ntawm koj uas ua electrophoresis feem ntau nco ntsoov qhov ntawd.
Lub npe Askiv ntawm alanine los ntawm German acetaldehyde, thiab Suav lub npe yog yooj yim to taub vim hais tias alanine muaj peb carbons thiab nws cov tshuaj npe yog alanine.Qhov no yog lub npe yooj yim, raws li yog lub cim ntawm cov amino acid.Lub sab saw ntawm alanine tsuas muaj ib pab pawg methyl thiab yog me ntsis loj dua li ntawm glycine.Thaum kuv kos cov qauv qauv rau lwm 18 amino acids, kuv ntxiv pab pawg rau alanine.Hauv cov proteins, alanine zoo li cib, cov khoom siv hauv tsev uas tsis muaj teeb meem nrog leej twg.
Lub sab saw ntawm alanine muaj me ntsis hindrance thiab nyob rau hauv lub α-helix, uas yog ib tug conformation.Nws kuj tseem ruaj khov thaum β-folded.Hauv kev tsim cov protein, yog tias koj xav hloov pauv cov amino acid yam tsis muaj lub hom phiaj tshwj xeeb ntawm cov protein, feem ntau koj tuaj yeem hloov mus rau alanine, uas tsis yooj yim los rhuav tshem tag nrho cov qauv ntawm cov protein.
Post lub sij hawm: May-29-2023