ACETYL-AMYLOID BETA / 289634-54-4 / GT Peptide / Peptide Supplier

Kev piav qhia

"Qhov no cyclic peptide homologous rau heparin-binding domain ntawm APP tau khi rau heparin thiab inhibits kev khi ntawm 12 I-labeled APP rau heparin (IC 50 = 10μM)."Qhov peptide no thaiv APP-vim heparan sulfate proteoglycan-dependent stimulation ntawm neurite outgrowth.Pom zoo li cov hmoov dawb, peptide yog chemically synthesized thiab tsuas yog siv rau kev tshawb fawb, tsis yog rau tib neeg siv.Cia tej yam kev mob nyob ntawm qhov tsis zoo 80° C rau negative 20° C.

Specifications

Apperance: Dawb mus rau dawb hmoov

Purity (HPLC):≥98.0%

Ib qho impurity:≤2.0%

Cov ntsiab lus Acetate (HPLC): 5.0%～12.0%

Cov ntsiab lus dej (Karl Fischer):≤10.0%

Cov ntsiab lus Peptide:≥80.0%

Packing thiab Shipping: Tsis tshua muaj kub, lub tshuab nqus tsev ntim, raug rau mg raws li xav tau.

Yuav Order li cas?

1. Contact us directly by phone or email: +86-13735575465, sales1@gotopbio.com.

2. Order online.Thov sau daim ntawv xaj online.

3. Muab lub npe peptide, CAS No. los yog ib ntus, purity thiab hloov kho yog tias xav tau, kom muaj nuj nqis, thiab lwm yam peb yuav muab cov lus hais hauv 2 teev.

4. Kev txiav txim kom haum raws li daim ntawv cog lus muag thiab NDA (tsis qhia tawm daim ntawv cog lus) lossis daim ntawv cog lus zais cia.

5. Peb yuav hloov kho qhov kev txiav txim tsis tu ncua raws sijhawm.

6. Peptide xa los ntawm DHL, Fedex lossis lwm tus, thiab HPLC, MS, COA yuav muab nrog rau cov khoom thauj.

7. Txoj cai them rov qab yuav ua raws li yog tias muaj qhov tsis sib xws ntawm peb qhov zoo lossis kev pabcuam.

8. Kev pab cuam tom qab muag: Yog tias peb cov neeg siv khoom muaj lus nug txog peb cov peptide thaum lub sijhawm sim, thov koj xav tiv tauj peb thiab peb yuav teb rau hauv lub sijhawm luv luv.

Tag nrho cov khoom ntawm lub tuam txhab tsuas yog siv rau kev tshawb fawb lub hom phiaj, nws's txwv tsis pub siv ncaj qha los ntawm ib tus neeg ntawm tib neeg lub cev.

FAQ:

Puas yog cov peptides uas muaj Cys txo qis ua ntej xa khoom?

Yog tias peptide tsis pom tias tau oxidized, peb feem ntau tsis txo Cys.Tag nrho cov polypeptides tau txais los ntawm cov khoom nyoos purified thiab lyophilized nyob rau hauv pH2 tej yam kev mob, uas tsawg kawg rau qee qhov kev tiv thaiv oxidation ntawm Cys.Peptides uas muaj Cys raug ntxuav ntawm pH2 tshwj tsis yog tias muaj ib qho laj thawj tshwj xeeb los ntxuav ntawm pH6.8.Yog tias kev ua kom huv huv ntawm pH6.8, cov khoom huv huv yuav tsum tau kho nrog cov kua qaub tam sim kom tiv thaiv oxidation.Hauv cov kauj ruam kawg tswj kev ua tau zoo, rau cov peptides uas muaj Cys, yog tias muaj cov khoom hnyav molecular (2P + H) pom nyob rau hauv daim ntawv qhia MS, nws qhia tau hais tias ib tug dimer tau tsim.Yog tias tsis muaj teeb meem nrog MS thiab HPLC, peb yuav ncaj qha lyophilize thiab xa cov khoom yam tsis muaj kev ua haujlwm ntxiv.Nws yuav tsum tau muab sau tseg tias peptides uas muaj Cys undergo qeeb oxidation lub sij hawm, thiab cov degree ntawm oxidation nyob ntawm peptide ib theem zuj zus thiab cia tej yam kev mob.

Yuav ua li cas koj txiav txim siab yog hais tias ib tug peptide yog looped?

Peb siv cov tshuaj tiv thaiv Ellman los ntsuas seb lub nplhaib tsim puas tiav.Yog tias qhov kev kuaj Ellman yog qhov zoo (daj), lub nplhaib cov tshuaj tiv thaiv tsis tiav.Yog tias qhov ntsuas tau tsis zoo (tsis yog daj), lub nplhaib cov tshuaj tiv thaiv tau ua tiav.Peb tsis muab cov ntaub ntawv txheeb xyuas ntawm kev txheeb xyuas cyclization rau peb cov neeg siv khoom.Feem ntau, yuav muaj cov lus piav qhia ntawm Ellman cov txiaj ntsig kev xeem hauv QC daim ntawv tshaj tawm.

Kuv xav tau ib tug cyclic peptide, uas muaj ib tug tryptophan, nws puas yuav oxidized?

oxidation ntawm tryptophan yog ib qho tshwm sim hauv peptide oxidation, thiab peptides feem ntau yog cyclized ua ntej purification.Yog tias oxidation ntawm tryptophan tshwm sim, lub sijhawm khaws cia ntawm peptide ntawm HPLC kem yuav hloov, thiab oxidation tuaj yeem raug tshem tawm los ntawm kev ua kom huv.Tsis tas li ntawd, oxidized peptides kuj tuaj yeem kuaj pom los ntawm MS.

Puas tsim nyog muab qhov sib txawv ntawm peptide thiab cov xim?

Yog tias koj yuav txuas lub molecule loj (xws li zas xim) rau peptide, nws yog qhov zoo tshaj plaws los muab qhov chaw nruab nrab ntawm peptide thiab ligand kom txo qis kev cuam tshuam nrog cov receptor los ntawm folding ntawm peptide nws tus kheej los yog folding. nws conjugate.Lwm tus tsis xav tau ib ntus.Piv txwv li, nyob rau hauv lub folding ntawm cov proteins, nws muaj peev xwm txiav txim siab nyob deb npaum li cas sib nrug ntawm lub folding qauv ntawm ib tug amino acid los ntawm kev txuas ib tug fluorescent dye rau ib qho chaw.

Yog tias koj xav ua qhov hloov kho biotin ntawm N davhlau ya nyob twg, koj puas yuav tsum tau muab qhov sib txawv ntawm biotin thiab peptide ib ntus?

Tus txheej txheem biotin daim ntawv lo siv los ntawm peb lub tuam txhab yog xa cov Ahx rau peptide saw, ua raws li biotin.Ahx yog 6-carbon compound uas ua raws li kev thaiv ntawm peptide thiab biotin.

Koj puas tuaj yeem muab qee cov lus qhia txog kev tsim cov phosphorylated peptides?

Raws li qhov ntev nce, qhov kev sib khi ua tau zoo maj mam txo qis los ntawm phosphorylated amino acid ntxiv mus.Kev taw qhia synthesis yog los ntawm C davhlau ya nyob twg mus rau N davhlau ya nyob twg.Nws raug nquahu tias cov seem tom qab phosphorylated amino acid yuav tsum tsis pub tshaj 10, uas yog, tus naj npawb ntawm cov amino acid residues ua ntej phosphorylated amino acid los ntawm N davhlau ya nyob twg mus rau C davhlau ya nyob twg yuav tsum tsis pub tshaj 10.

Vim li cas n-terminal acetylation thiab C-terminal amidation?

Cov kev hloov kho no tiv thaiv peptide los ntawm kev degraded thiab tso cai rau peptide ua raws li nws lub xeev qub ntawm alpha amino thiab carboxyl pawg hauv niam txiv cov protein.