Thaum lub sij hawm peptide synthesis, ib co ntsev yuav tsum tau ntxiv.Tab sis muaj ntau hom ntsev, thiab ntau hom ntsev ua cov peptides sib txawv, thiab cov nyhuv tsis zoo ib yam.Yog li niaj hnub no peb tsuas yog xaiv hom peptide ntsev uas tsim nyog hauv peptide synthesis.
1. Trifluoroacetate (TFA): Qhov no yog cov ntsev uas nquag siv hauv cov khoom peptide, tab sis nws yuav tsum tau zam hauv qee qhov kev sim vim yog biotoxicity ntawm trifluoroacetate.Piv txwv li, kev sim ntawm tes.
2. Acetate (AC): Lub biotoxicity ntawm acetic acid yog tsawg dua trifluoroacetic acid, yog li feem ntau cov kws kho mob thiab cov tshuaj pleev ib ce peptides siv acetate, tab sis qee cov khoom muaj cov acetate tsis ruaj khov, yog li qhov kev ruaj ntseg ntawm qhov sib lawv liag kuj yuav tsum tau xav txog.Acetate tau raug xaiv rau feem ntau cov kev sim ntawm tes.
3. Hydrochloric acid (HCL) : Cov ntsev no tsis tshua muaj kev xaiv, thiab tsuas yog qee cov kab ke siv hydrochloric acid rau lub hom phiaj tshwj xeeb.
4. Ammonium ntsev (NH4+): Cov ntsev no yuav cuam tshuam rau kev solubility thiab stability ntawm cov khoom, yuav tsum tau xaiv nyob rau hauv kev txiav txim.
5. Sodium ntsev (NA+): nws feem ntau cuam tshuam rau kev ruaj ntseg thiab solubility ntawm cov khoom.
6. Pamoicacid: Cov ntsev no feem ntau siv hauv cov tshuaj peptide los ua cov tshuaj tiv thaiv-tso tawm.
7. CitricAcid: Cov ntsev no muaj cov tshuaj lom neeg lub cev me me, tab sis nws qhov kev npaj yog qhov nyuaj heev, yog li cov txheej txheem tsim khoom yuav tsum tau tsim ua ntu zus thiab sib cais.
8. Salicylicacid: Salicylate tuaj yeem cuam tshuam qhov ruaj khov ntawm cov khoom peptide, yog li nws tsis tshua siv.
Cov saum toj no yog ob peb hom peptide ntsev, thiab peb kuj yuav tsum xaiv raws li cov yam ntxwv ntawm cov ntsev sib txawv hauv kev siv tiag tiag.
Post lub sij hawm: Jun-16-2023