Hais txog peb:
Lub peptide yog cov saw hlau ntawm cov amino acids txuas los ntawm peptide bonds.Peptides feem ntau koom nrog hauv kev tswj hwm cov protein, angiogenesis, cell proliferation, melanogenesis, cell migration, thiab o.Bioactive peptides tau siv dav hauv kev lag luam tshuaj pleev ib ce nyob rau xyoo tsis ntev los no.Peptides yuav tsum tsis muaj qhov hnyav molecular (> 500 Da), txhawm rau txo qhov diffusion ntawm peptide ntawm cov txheej txheem epidermal, siab ruaj khov thiab solubility.Tau ntau xyoo, cov zej zog kev tshawb fawb tau tsim ib qho me me thiab ruaj khov peptide fragment uas ua kom muaj collagen ntau lawm thiab txo cov ntsej muag wrinkles thiab pigmentation.Trifluoroacetyl tripeptide-2 (ib ntus: TFA-Val-Try-Val-OH) tripeptide synthesis, tsim los ua matrix metalloproteinase thiab elastase inhibitor.Hauv vitro kev tshawb fawb txog kev tiv thaiv ECM los ntawm trifluoro-acetyl tripeptide 2 (TT2), kev sib xyaw ntawm proteoglycan hauv kev sib cuam tshuam ntawm tes-matrix, thiab cov txiaj ntsig ntawm progerin synthesis hauv cov neeg laus laus laus fibroblasts tau raug txheeb xyuas tsis ntev los no tias yog ib qho co-inducer ntawm cellular. kev laus.Cov txiaj ntsig tau qhia tias trifluoroacetyl tripeptide 2 muaj ntau yam kev tiv thaiv kev laus.Qhov no txo qis progerin synthesis, tsub kom proteoglycan ntau lawm, thiab shrinks collagen, yog li txo wrinkles thiab txhim kho cov nqaij ntshiv.Tsis tas li ntawd, nws cov kev tiv thaiv-wrinkling, tiv thaiv ntws dai thiab cov tawv nqaij zawm cov teebmeem raug soj ntsuam hauv ob qho hauv vitro cais lub ntsej muag kev tshawb fawb.Trifluoroacetyl tripeptide 2 tau pom tias muaj kev cuam tshuam loj ntawm wrinkles, nruj, elasticity, thiab sagging.
Trifluoroacetyl tripeptide-2 puas tuaj yeem ncua kev laus?
Cov kev tshawb fawb tau pom tias cell senescence yog ze ze rau Progerin.Nrog rau kev laus, presenilin accumulates ntau thiab ntau nyob rau hauv lub cev, ua rau nuclear defects thiab DNA puas, ua rau ntau yam ntawm daim tawv nqaij laus.Trifluoroacetyl tripeptide-2 yog ib qho active tripeptide ntawm Elafin, derivative ntawm elastase inhibitor.Nws txo Progerin synthesis thiab txhim kho daim tawv nqaij laxity, sagging thiab wrinkles.
Mechanism
1. inhibit qhov synthesis ntawm Progerin kom ncua cellular senescence.
2. Txhawb syndecan ntau lawm thiab ua kom lub neej ntev ntawm tes.
3. inhibit qhov kev ua ntawm matrix metalloproteinases MMP1, MMP3 thiab MMP9, txo qhov kev tawg ntawm extracellular matrix proteins thiab tswj lawv cov kev ncaj ncees.
4. inhibit elastase kev ua, txo elastin degradation, thiab ua kom tawv nqaij nruj thiab elastic dua.
Daim ntawv thov
Nws yog tsim rau txhua yam kev tiv thaiv wrinkle thiab anti-aging, firming kho, anti-photoaging, post-natal thiab post-hnub lub cev tu, thiab lwm yam. Nws yog ntxiv nyob rau hauv lub kawg theem ntawm cov tshuaj pleev ib ce ntau lawm
Post lub sij hawm: May-22-2023