Cov lus qhia luv luv rau tidulutide

Mechanism ntawm kev txiav txim ntawm tidulutide Gatex (teduglutide)

Teduglutide yog ib tug tib neeg analogue ntawm glucagon-zoo li peptide-2 (GLP-2), peptide secreted los ntawm L hlwb nyob rau hauv lub plab distal.GLP-2 paub tias txhim kho plab hnyuv thiab portal ntshav txaus thiab inhibit gastric acid secretion.Rau qib ntawm lu peptide thiab peptide receptor 2 glucagon kuaj, insulin zoo li kev loj hlob zoo hauv cov hnyuv endocrine hlwb, cov hlwb epithelial ntawm cov leeg nqaij fiber ntau, submucosa thiab myenteric sawv ntawm txoj hnyuv neurons.Kev ua kom cov receptors no ua rau hauv zos tso tawm ntau yam xov xwm, suav nrog insulin-zoo li kev loj hlob zoo (IGF) 1, cell loj hlob yam tsim nitrogen oxide thiab cutin cell loj hlob yam (KGF).

Tidulutide, ib qho glucagon-zoo li peptide 2 (GLP-2) analogue, txo cov plab hnyuv plab thiab cov metabolism thiab tswj kev loj hlob, kev tsim tawm thiab rov ua kom cov kab mob hauv plab hnyuv.Peptide nce tag nrho cov hlwb ntawm cov hlwb, tuaj yeem ua rau kom nqus tau cov hnyuv, txo cov plab hnyuv.Short plob tsis so tswj nyob rau hauv cov neeg laus tuaj yeem kho.Cov tshuaj tau dhau los ua thawj cov tshuaj pom zoo rau qhov tsis tshua muaj tab sis tsis muaj zog heev.

Cov lus qhia luv luv rau tidulutide

Tshuaj molecular mis ntawm tidulutide

Basic tsis

Lub npe: rau c peptide (Teduglutide)

Qauv Zauv: GT-F027

CAS Nr .: 197922-42-2

Sequence: His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn- Trp-Leu-Ile-Gln-Thr-Lys- Ile-Thr-Asp

Cov mis mos molecular: C164H252N44O55S

Molecular Luj: 3752.08248